A patient with a family history of breast cancer wants to know her risk of having breast cancer. Which of the following genes should be analyzed in this patient?

Question

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BRCA1 is a gene that, when mutated, increases the risk of breast and ovarian cancer. A patient with a family history of breast cancer may have inherited a mutation in BRCA1, and therefore should be analyzed for this gene. Von Hippel-Lindau, N-myc, and K-ras are not associated with an increased risk of breast cancer.

A Patient with a Family History of Breast Cancer Wants