PolyT oligomers bound to a matrix resin column will selectively isolate which of the following?

Question

Quizplus · Accepted Answer

PolyT oligomers are composed of thymine nucleotides, which specifically bind to the polyA tail of mRNA molecules. Therefore, a column of polyT oligomers bound to a matrix resin will selectively isolate mRNA from a mixture of nucleic acids. Ribosomal RNA (A) and transfer RNA (C) do not have a polyA tail and are not selectively bound by polyT oligomers. GC-rich DNA (B) is not specifically targeted by polyT oligomers.

PolyT Oligomers Bound to a Matrix Resin Column Will Selectively