Which anticoagulant is preferred for diagnostic procedures that analyze DNA since it does not inhibit the action of restriction endonucleases?

Question

Quizplus · Accepted Answer

Ethylenediaminetetraacetic acid (EDTA) is the preferred anticoagulant for diagnostic procedures that analyze DNA since it chelates calcium ions, preventing coagulation, but does not inhibit the action of restriction endonucleases. Heparin can inhibit the action of restriction endonucleases by binding to the co-factor required for their activity, while sodium fluoride and calcium oxalate are not commonly used as anticoagulants for DNA analysis.

Which Anticoagulant Is Preferred for Diagnostic Procedures That Analyze DNA