In patients with severe von Willebrand's disease (vWD), aggregation to __________ is characteristically severely reduced or absent.

Question

Quizplus · Accepted Answer

Aggregation to Ristocetin is specifically impaired in severe vWD due to the deficiency of von Willebrand factor (vWF), which plays a crucial role in platelet function by binding to both platelet glycoprotein Ib and collagen, and thus mediates platelet adhesion and aggregation.

In Patients with Severe Von Willebrand's Disease (VWD), Aggregation to __________