A thrombin time test was performed and the resulting clotting time exceeded the reference range. A 1:1 mixing study with normal pooled plasma was done that corrected the result to the normal range. Which abnormality is suspected?

Question

Quizplus · Accepted Answer

The correction of the clotting time to the normal range after a 1:1 mixing study with normal pooled plasma suggests a deficiency in a clotting factor, in this case, fibrinogen deficiency. This is because the addition of normal plasma provides the deficient factor (fibrinogen), thereby correcting the clotting time.

A Thrombin Time Test Was Performed and the Resulting Clotting