Which hemolytic condition demonstrates complete hemolysis at 0.45% with the osmotic fragility test, and contains RBCs with a decreased surface-to-volume ratio?

Question

Quizplus · Accepted Answer

Hereditary spherocytosis is the only condition that demonstrates complete hemolysis at 0.45% with the osmotic fragility test and has RBCs with a decreased surface-to-volume ratio. Acquired hemolytic anemia, HDN, sickle cell anemia, and thalassemia do not typically show decreased surface-to-volume ratios.

Which Hemolytic Condition Demonstrates Complete Hemolysis at 0