Which of the Following Statements About Hyperhomocysteinemia Is/are True

Which of the following statements about hyperhomocysteinemia is/are true?

A) Hyperhomocysteinemia can be inherited or acquired.
B) Deficiencies of folate, vitamin B₆, and vitamin B₁₂ can cause hyperhomocysteinemia.
C) Mutation in the methylene tetrahydrofolate reductase (MTHFR) gene is responsible for some forms of hyperhomocysteinemia.
D) Mild to moderate hyperhomocysteinemia is an independent risk factor for arterial thrombotic diseases such as stroke, myocardial infarction, and peripheral vascular disease.
E) All of the above