In trying to explain a prolonged APTT, the following should be considered:

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All of the above are possible causes of a prolonged APTT and should be considered when interpreting the results. Heparin contamination, hypofibrinogenemia/DIC, increased anticoagulant due to elevated hematocrit or traumatic venipuncture, and specific factor deficiencies or inhibitors can all affect the APTT result. Therefore, it is important to review the clinical history and perform additional testing to determine the cause and appropriate management.

In Trying to Explain a Prolonged APTT, the Following Should