Unfractionated heparin (UH) therapy:

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Unfractionated heparin therapy requires frequent monitoring, typically every 6 hours initially, until the therapeutic interval has been achieved. After that, daily monitoring is usually sufficient. This is because UH has a narrow therapeutic interval and individual dosing is required to achieve optimal anticoagulation while minimizing the risk of bleeding or thrombosis. UH can be given by both intravenous and subcutaneous routes. Monitoring of UH can be done via the APTT, but additional tests may be required depending on the clinical situation.

Unfractionated Heparin (UH) Therapy