The etiology of Glanzmann's thrombasthenia results from the inability of __________ to bind to platelet surface membranes, which would normally result in aggregation.

Question

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Glanzmann's thrombasthenia is caused by a deficiency or dysfunction of the glycoprotein IIb/IIIa complex, which is responsible for binding to fibrinogen and enabling platelet aggregation. Therefore, the inability of fibrinogen to bind to platelet surface membranes leads to the condition. Plasmin, thrombin, and calcium are not directly involved in platelet aggregation through the IIb/IIIa complex.

The Etiology of Glanzmann's Thrombasthenia Results from the Inability of __________