In a woman who presents in her first trimester of her first pregnancy with a platelet count of 80 $\times$ 10⁹/L, you must consider which of the following diagnoses?

Question

Quizplus · Accepted Answer

A platelet count of 80 x 10^9/L in the first trimester of pregnancy is below the normal range and requires further evaluation. The most likely diagnosis in this case would be immune thrombocytopenic purpura (ITP), which presents with isolated thrombocytopenia in pregnancy. Gestational thrombocytopenia can also cause a mild decrease in platelet count, but it typically does not fall below 100 x 10^9/L and is a diagnosis of exclusion. Eclampsia (HELLP syndrome) can cause a low platelet count, but it typically presents in the third trimester and is associated with elevated liver enzymes and hemolysis. Folic acid deficiency is not typically associated with a low platelet count. Therefore, the best choice in this scenario is B) ITP.

In a Woman Who Presents in Her First Trimester of Her