One factor that distinguishes true Gaucher cells from pseudo-Gaucher cells is:

Question

Quizplus · Accepted Answer

True Gaucher cells are characterized by a deficiency in the enzyme β-glucocerebrosidase, which results in the accumulation of glucocerebroside in the lysosomes. Pseudo-Gaucher cells, on the other hand, are macrophages that accumulate glucocerebroside due to phagocytosis of damaged or dying cells in a variety of conditions. Therefore, the deficiency in β-glucocerebrosidase is a distinguishing factor between true Gaucher cells and pseudo-Gaucher cells. Cell size, morphological characteristics, and acid phosphatase levels may be similar between the two.

One Factor That Distinguishes True Gaucher Cells from Pseudo-Gaucher Cells