Which variant of multiple myeloma produces a malignant clone of plasma cells that are too immature to secrete immunoglobulins and does not produce an M-spike by electrophoretic studies?

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Nonsecretory myeloma is a variant of multiple myeloma in which there is a malignant clone of plasma cells that are too immature to secrete immunoglobulins and do not produce an M-spike by electrophoretic studies. This type of myeloma is diagnosed based on other laboratory and imaging findings, such as anemia, hypercalcemia, bone lesions, and elevated serum levels of beta-2 microglobulin and lactate dehydrogenase.

Which Variant of Multiple Myeloma Produces a Malignant Clone of Plasma