Which MDS classification has the best prognosis?

Question

Quizplus · Accepted Answer

RA (Refractory Anemia) has the best prognosis among the MDS classifications as it is defined by the presence of <5% blasts in the bone marrow, no Auer rods, and no evidence of AML. RAEB-T (Refractory Anemia with Excess Blasts in Transformation) has the worst prognosis, with >20% blasts in the blood or bone marrow, and it is considered as a progression towards AML. RAEB (Refractory Anemia with Excess Blasts) is also associated with a poor prognosis, with the presence of 5-19% blasts in the blood or bone marrow. CMML (Chronic Myelomonocytic Leukemia) is classified as an overlap syndrome between MDS and myeloproliferative neoplasms and has an intermediate prognosis.

Which MDS Classification Has the Best Prognosis