A 35-year-old man presents with anemia, neutropenia, thrombocytopenia, myeloblasts with the presence of Auer rods, and one or two distinct nucleoli and promyelocytes. Cytochemistry examination demonstrates peroxidase and Sudan black B (SBB) positive and TdT terminal deoxynucleotidyl transferase (TdT) negative. This hematologic picture is consistent with:

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The hematologic picture described is consistent with acute myeloblastic leukemia (AML) based on the presence of myeloblasts with Auer rods, neutropenia, thrombocytopenia, anemia, peroxidase and SBB positivity, and TdT negativity. The presence of distinct nucleoli and promyelocytes may indicate a specific subtype of AML called acute promyelocytic leukemia (APL). APL is characterized by the presence of abnormal promyelocytes with distinctive morphology, including abundant azurophilic granules and multiple Auer rods.

A 35-Year-Old Man Presents with Anemia, Neutropenia, Thrombocytopenia, Myeloblasts with the Presence