The SBB stain is the most sensitive stain for granulocytic precursors with a staining pattern which parallels the __________ stain.

Question

Quizplus · Accepted Answer

The SBB stain (Sudan Black B) is used to detect myeloperoxidase activity in granulocytic precursors. Myeloperoxidase (MPO) is an enzyme contained within the primary granules of the cytoplasm of neutrophils, eosinophils, and basophils. Therefore, the staining pattern observed with the SBB stain parallels that of the MPO stain. A) Terminal deoxynucleotidyl transferase (TdT) is detected by the TdT stain and is used to identify lymphoid precursors. B) The Periodic acid-Schiff (PAS) stain is used to detect carbohydrates and is often used to diagnose glycogen storage diseases. D) Alpha-naphthyl butyrate (ANB) is used to detect esterase activity and is often used to identify monocytes and monocytic precursors.

The SBB Stain Is the Most Sensitive Stain for Granulocytic