Promyelocytes constitute 10% of this acute leukemia with more than 50% of leukemia cells positive for peroxidase or SBB. What is the FAB leukemia classification?

Question

Quizplus · Accepted Answer

The presence of promyelocytes and more than 50% of leukemia cells positive for peroxidase or SBB indicates acute myeloid leukemia (AML). The FAB classification system is a way to categorize different types of AML based on the morphology and cytochemistry of the leukemia cells. In this case, the presence of promyelocytes suggests a myeloid origin, and the high percentage of positive peroxidase or SBB staining indicates a myeloblastic subtype. This fits the criteria for FAB M2 classification, which is characterized by the presence of blasts with differentiation along the myeloid lineage, including promyelocytes.

Promyelocytes Constitute 10% of This Acute Leukemia with More Than