Shortened red cell survival in anemia of inflammation may be due to:

Question

Quizplus · Accepted Answer

Anemia of inflammation is characterized by shortened red cell survival, which may be due to the extracorpuscular effects of activated macrophage-monocytes of the reticuloendothelial system (RES). These cells may increase red cell destruction by phagocytosis, sequestering red cells in the RES, and inducing iron sequestration. Autoantibodies, defective membrane, decreased protoporphyrin synthesis, and intravascular hemolysis are not commonly associated with anemia of inflammation.

Shortened Red Cell Survival in Anemia of Inflammation May Be