Which of the following is characteristic of HbC disease?

Question

Quizplus · Accepted Answer

HbC disease is an inherited blood disorder caused by a mutation in the HBB gene. It results in the production of abnormal hemoglobin C, which can cause a mild chronic hemolytic anemia. Splenomegaly may also occur as the spleen's job is to remove damaged red blood cells from the circulation. Normocytic, normochromic anemia with numerous target cells (50-90%) and occasional folded cells is a typical finding on a blood smear. Additionally, Hemoglobin C ("bar of gold") crystals may be present on the blood smear of splenectomized patients. Therefore, option E "All of the above" is the correct answer.

Which of the Following Is Characteristic of HbC Disease