Which of the following RBC metabolic pathways is responsible for the production of the organic phosphate 2,3-DPG, which is important in delivering oxygen to the tissues?

Question

Quizplus · Accepted Answer

The Luebering-Rapaport pathway is responsible for the production of 2,3-DPG in RBCs. This pathway involves the conversion of 1,3-bisphosphoglycerate to 2,3-DPG by the enzyme bisphosphoglycerate mutase. 2,3-DPG binds to hemoglobin and lowers its affinity for oxygen, which enhances oxygen delivery to the tissues. The Embden-Meyerhof pathway and the hexose monophosphate pathway are involved in energy production and the maintenance of redox balance in RBCs. The methemoglobin reductase pathway is involved in the reduction of methemoglobin to hemoglobin.

Which of the Following RBC Metabolic Pathways Is Responsible for the Production