Which of the following describes biochemical changes that occur in the intervertebral disc with aging?
A) Increased proteoglycan concentration in the nucleus pulposus
B) Increased water-binding capacity
C) Increased collagen content in nucleus pulposus
D) Increased elastin content in the anulus fibrosis

Question

Quizplus · Accepted Answer

With aging, the intervertebral disc undergoes several biochemical changes, including an increase in collagen content in the nucleus pulposus. This change contributes to the disc's decreased ability to handle mechanical stress and its increased susceptibility to degeneration. Proteoglycan concentration and water-binding capacity typically decrease, not increase, and elastin content changes are not characteristic of aging in the intervertebral disc.

Which of the Following Describes Biochemical Changes That Occur in the Intervertebral