When performing flow cytometry, the technologist interpreted the flow pattern as exhibiting a high degree of CD14- and CD4-positive cells.The peripheral smear showed large multilobulated blast cells.This pattern is most representative of:

Question

Quizplus · Accepted Answer

AMonoL, or Acute Monoblastic Leukemia, is characterized by the presence of large numbers of monoblasts in the blood. The high degree of CD14- and CD4-positive cells is indicative of monoblastic lineage, as CD14 is a monocyte marker and CD4 can be expressed on monocytes and their precursors. The description of large multilobulated blast cells in the peripheral smear further supports this diagnosis, as these are typical features of monoblasts in Acute Monoblastic Leukemia.

When Performing Flow Cytometry, the Technologist Interpreted the Flow Pattern