Tetrodotoxin from puffer fish interferes with the formation of action potentials by blocking
A) voltage-dependent sodium channels.
B) voltage-dependent potassium channels.
C) ligand-gated sodium channels.
D) ligand-gated potassium channels.

Question

Quizplus · Accepted Answer

Tetrodotoxin from puffer fish blocks voltage-dependent sodium channels, which are responsible for the influx of sodium ions and the depolarization phase of the action potential. By blocking these channels, tetrodotoxin effectively inhibits the formation of action potentials in neurons and can lead to paralysis or even death in animals that consume it. It does not block voltage-dependent potassium channels or ligand-gated sodium or potassium channels.

Tetrodotoxin from Puffer Fish Interferes with the Formation of Action