The "headache generator" sends messages to the meninges and blood supply via the release of
A) GABA by the vagus nerve.
B) dopamine by the facial nerve.
C) serotonin by the hypoglosseal nerve.
D) CGRP by the trigeminal nerve.

Question

Quizplus · Accepted Answer

CGRP (calcitonin gene-related peptide) is known to be a potent vasodilator and can increase the permeability of blood vessels. It is released by trigeminal nerve fibers that innervate the meninges and blood vessels in the brain, and is thought to play a key role in the development of migraine headaches. GABA, dopamine, and serotonin are all neurotransmitters involved in various physiological processes, but none of them are specifically linked to the headache-generating mechanisms in the brain.

The "Headache Generator" Sends Messages to the Meninges and Blood