The most appropriate first-line treatment for an acute gout flare is (assuming no kidney disease or elevated bleeding risk):

Question

Quizplus · Accepted Answer

Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) and is considered first-line treatment for acute gout flares. It works by reducing inflammation and pain associated with the flare. The dosing regimen mentioned in option A is a commonly used regimen. Option B is not a recommended treatment for acute gout flares. Prednisolone is a steroid and can be used as an alternative to NSAIDs, but is not typically first-line. Ice therapy may provide some relief for symptoms, but is not considered first-line treatment.

The Most Appropriate First-Line Treatment for an Acute Gout Flare