What part of the chromosome is thought to be the location where cells lose their ability to replicate?

Question

Quizplus · Accepted Answer

Telomeres are repetitive DNA sequences located at the ends of chromosomes that protect them from degradation and fusion with neighboring chromosomes. However, during each round of cell division, a small portion of the telomeric DNA is lost, eventually resulting in critically short telomeres that trigger cellular senescence or cell death. This loss of telomeres is thought to be the mechanism by which cells lose their ability to replicate, leading to aging and age-related diseases.

What Part of the Chromosome Is Thought to Be the Location