Cytotoxic T cells respond only to antigens bound to MHC-I proteins.

Name: Cytotoxic T cells respond only to antigens bound to MHC-I proteins.
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Cytotoxic T cells, also known as CD8+ T cells, recognize and respond to antigens that are presented on the surface of cells by MHC-I proteins. They are able to recognize and destroy cells that have become infected with a virus or other intracellular pathogen, as well as cells that have become cancerous or abnormal in other ways.

Cytotoxic T Cells Respond Only to Antigens Bound to MHC-I