A person with type O positive blood receives a transfusion of type B negative blood. What will happen?

Question

Quizplus · Accepted Answer

Type O blood has no A or B antigens on the surface of its red blood cells, but it does have anti-A and anti-B antibodies in the plasma. Type B blood has B antigens on the surface of its red blood cells, and anti-A antibodies in the plasma. Since the recipient has anti-B antibodies in their plasma, these antibodies will recognize the B antigens on the surface of the transfused type B blood and target them for destruction. This can result in a potentially life-threatening transfusion reaction. Therefore, it is important to match blood types appropriately to avoid such reactions.

A Person with Type O Positive Blood Receives a Transfusion