Which of the Following Statements Are True of a Fever

Which of the following statements are true of a fever (Select all that apply) ?

A) A substance or pathogen that causes a fever is a pyrogen.
B) A low fever may be beneficial in that WBCs become more active.
C) A pyrogen activates the heat gain mechanisms regulated by the thalamus.
D) A very high fever may cause brain damage because carbohydrates become denatured.
E) Some chemicals produced as part of inflammation are endogenous pyrogens.
F) A fever may be beneficial in that a higher temperature inhibits some bacteria.