A Diabetic 68-Year-Old Female Patient Arrives at the Clinic with a History

A diabetic 68-year-old female patient arrives at the clinic with a history of smoking, hypertension, family history of cardiac disease, COPD, and infrequent exercise. The nurse identifies which of these as the most significant risk factors for peripheral arterial disease (PAD) ?

A) COPD and family history of cardiac disease
B) Age and gender
C) Sedentary lifestyle and diabetes
D) Hypertension and smoking