A patient is diagnosed with systemic lupus erythematosus (SLE) .What does the nurse understand is included in the pathophysiology that occurs in this autoimmune disorder?
A) Systemic tissue destruction initiated by sensitized T cells attacking DNA antigens and releasing lymphokines
B) A deficiency of T suppressor (CD8) cells,allowing unchecked destruction of all organ tissue by T cytotoxic cells
C) Activation of the complement cascade as a result of IgM binding with viral antigens,causing cytolysis of vascular tissue
D) DNA released into the circulation and reacting with an antibody
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