When the same dose of a drug no longer produces the desired effect, it is said that the patient has developed

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Drug tolerance is when the same dose of a drug no longer produces the desired effect. This can occur when the body becomes accustomed to the presence of the drug and requires higher doses to achieve the same effect. An idiosyncratic reaction is a rare and unpredictable adverse reaction to a drug. An allergic reaction occurs when the body's immune system reacts abnormally to a drug. A drug interaction is when two or more drugs interact with each other, either enhancing or diminishing the effects of the drugs.

When the Same Dose of a Drug No Longer Produces