Gaucher Disease Is a Genetic Disorder in Which the Cells

Gaucher disease is a genetic disorder in which the cells do not produce an enzyme necessary for breaking down fatty substances.Persons afflicted with Gaucher disease experience severe problems, including swelling, bruising, anemia, neurological problems, and bone abnormalities.Some patients die of the disease.Which statement explains why the lack of an enzyme leads to the problems observed in patients with Gaucher disease?

A) Fatty substances accumulate and block normal cell functions.
B) Cells are forced to use fatty substances as a nutrient source.
C) DNA mutates at a greater rate upon exposure to fatty substances.
D) Fatty substances break down proteins and DNA in cells.
E) Enzymes other than the missing one catalyze their reactions at accelerated rates.