Peeling Skin Syndrome Is a Disease in Which Outer Skin

Peeling skin syndrome is a disease in which outer skin tissue peels off in large sheets in affected individuals.This disease has a genetic basis.Research has identified that patients with this disease produce a nonfunctional protein.This protein normally becomes embedded in skin cell membranes and functions in adhesion between cells to hold them together to stabilize skin tissue.Continued investigation into this disease would likely focus on locating the _______ in the gene encoding the nonfunctioning adhesion protein in these patients.