A cancer drug is being tested, and it is found that although the cancer cells can divide, the nuclear envelope cannot re-form.It is determined that a protein substance is sequestered so that it cannot be polymerized into the necessary structure.What is the most likely protein target of the drug?
A) Lamin
B) Keratin
C) α-tubulin
D) β-tubulin
E) Actin

Question

Quizplus · Accepted Answer

Lamin is a protein that plays a critical role in the formation and maintenance of the nuclear envelope. If this protein is sequestered and cannot be polymerized into the necessary structure, the nuclear envelope cannot reform properly. Therefore, inhibition of lamin could be the protein target of the cancer drug being tested. Keratin is a structural protein present in cells, but it is not directly involved in nuclear envelope formation. α-tubulin, β-tubulin, and actin are all involved in cytoskeleton formation and are not directly involved with nuclear envelope formation.

A Cancer Drug Is Being Tested, and It Is Found