A researcher finds that mouse kidney cells and mouse muscle cells both use cAMP as a second messenger in two different signal transduction pathways that result in different cellular responses.Which other condition related to these two pathways would be expected in these cells?
A) Both cells have the same cell surface receptor for the two pathways.
B) One cell has a cell surface receptor and the other has an intracellular receptor for these pathways.
C) Both pathways in the two cells have the same target protein whose activity changes when it binds cAMP.
D) Both cell types express the adenylate cyclase gene.
E) One pathway involves cAMP inhibition of a target protein, while the other pathway involves cAMP activation of a target protein.

Question

Quizplus · Accepted Answer

The presence of cAMP as a second messenger in both pathways suggests that both cell types must have the capability to produce cAMP, which is synthesized from ATP by the enzyme adenylate cyclase. Therefore, both cell types expressing the adenylate cyclase gene is a condition that would be expected.

A Researcher Finds That Mouse Kidney Cells and Mouse Muscle