Which represents the correct ordering from lowest number to highest number of molecules in a liver cell activated by a single molecule of epinephrine?
A) cAMP, protein kinase A, phosphorylase kinase, glycogen phosphorylase
B) Glycogen phosphorylase, phosphorylase kinase, protein kinase A, cAMP
C) cAMP, phosphorylase kinase, glycogen phosphorylase, protein kinase A
D) Glycogen phosphorylase, cAMP, protein kinase A, phosphorylase kinase
E) Phosphorylase kinase, glycogen phosphorylase, cAMP, protein kinase A

Question

Quizplus · Accepted Answer

The correct order from lowest to highest number of molecules in a liver cell activated by a single molecule of epinephrine reflects the signal amplification cascade. cAMP is produced first and in relatively low numbers. It activates protein kinase A, which then activates phosphorylase kinase, and finally, glycogen phosphorylase is activated in the highest numbers. This sequence represents the amplification of the signal from a single molecule of epinephrine through the cascade.

Which Represents the Correct Ordering from Lowest Number to Highest