Which statement about intracellular receptors that respond to physical or chemical signals is false?
A) Their ligands can be nonpolar molecules.
B) The estrogen receptor is intracellular.
C) Their chemical ligands are lipid-insoluble.
D) Light can excite intracellular receptors.
E) Intracellular receptors can be transcription factors.

Question

Quizplus · Accepted Answer

Intracellular receptors that respond to physical or chemical signals can have ligands that are lipid-soluble, so statement C is false. Their ligands can be nonpolar molecules and may include hormones, drugs, and other signaling molecules. The estrogen receptor is an example of an intracellular receptor that responds to a hormone. In addition, intracellular receptors can function as transcription factors, and their activation can lead to changes in gene expression. Light can also activate some intracellular receptors, such as the visual pigment rhodopsin in the eye.

Which Statement About Intracellular Receptors That Respond to Physical or Chemical