When a cell needs energy, cellular respiration is regulated by isocitrate dehydrogenase, an enzyme of the citric acid cycle.This enzyme is stimulated in part by

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Isocitrate dehydrogenase is stimulated by ADP. When the cell requires energy, the concentration of ADP increases, which in turn activates isocitrate dehydrogenase to initiate the citric acid cycle and produce ATP through cellular respiration.

When a Cell Needs Energy, Cellular Respiration Is Regulated by Isocitrate