Which situation has the highest potential for causing cancer?
A) A mutation in the p53 protein that causes it to become inactive, and a mutation in the RB protein that renders it overly active
B) A mutation in the p53 protein that causes it to become overly active, and a mutation in the RB protein that renders it inactive
C) Increased production of normal HER2, and a mutation in the RB protein that renders it inactive
D) Increased production of normal HER2, and a mutation in the RB protein that renders it overly active
E) Increased production of normal p53 protein, and a mutation in the RB protein that renders it inactive

Question

Quizplus · Accepted Answer

A mutation in the RB protein that renders it inactive can lead to uncontrolled cell division, and increased production of normal HER2 can promote cell proliferation. Together, these factors significantly increase the risk of cancer development.

Which Situation Has the Highest Potential for Causing Cancer