In the 1920s, a dye (now called Feulgen stain) was developed that bound DNA in direct proportion to the amount of DNA present in cells.Upon binding, the DNA would turn a bright purple.This DNA staining technique

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The Feulgen stain provided circumstantial evidence for DNA being the genetic material because it showed that DNA was present in the nucleus of cells where genetic material was known to be located. However, it did not definitively prove that DNA was the genetic material. It was later experiments, such as those with bacterial transformation by Griffith and the Hershey-Chase experiments with bacteriophages, that confirmed DNA as the genetic material.

In the 1920s, a Dye (Now Called Feulgen Stain) Was