Which statement about DNA replication pertains specifically to synthesis of the leading strand?
A) Okazaki fragments are synthesized as part of the lagging strand.
B) Replication forks represent areas of active DNA synthesis on the chromosomes.
C) DNA replication progresses in the direction of the acting helicase.
D) Ligases and polymerases function in the vicinity of replication forks.
E) The sliding clamp increases the rate of DNA synthesis.

Question

Quizplus · Accepted Answer

DNA replication on the leading strand progresses in the direction of the acting helicase, which unwinds the DNA helix. This allows continuous synthesis of the leading strand, in contrast to the discontinuous synthesis of the lagging strand, which involves Okazaki fragments.

Which Statement About DNA Replication Pertains Specifically to Synthesis of the Leading