Garrod Postulated That Alkaptonuria and Other Inborn Errors of Metabolism

Garrod postulated that alkaptonuria and other inborn errors of metabolism were due to

A) a defect in RNA corresponding to a defect in a single gene.
B) a defect in a single enzyme that corresponds to a defect in a single gene.
C) a defect in a single enzyme that corresponds to defects in several genes.
D) defects in several enzymes that correspond to a defect in a single gene.
E) defects in several enzymes that correspond to defects in several genes.