Consider the experiments by Noller and colleagues.If removal of proteins from the large subunit of the ribosome had destroyed peptidyl transferase activity, then one could infer that
A) rRNA is responsible for the breaking of bonds between tRNA and amino acids.
B) proteins are responsible for the breaking of bonds between tRNA and amino acids.
C) rRNA is responsible for the fidelity function.
D) tRNA is responsible for the fidelity function.
E) proteins are responsible for the fidelity function.

Question

Quizplus · Accepted Answer

If removing proteins from the large subunit of the ribosome destroyed peptidyl transferase activity, it would suggest that proteins are necessary for this enzymatic activity, rather than rRNA. Therefore, choice B is the best option as it suggests that proteins are responsible for breaking the bonds between tRNA and amino acids. The other options are not supported by this experiment.

Consider the Experiments by Noller and Colleagues