Sequencing of a child's genomic DNA reveals that the child is a heterozygote for a new mutation.This mutation appears in all of the cells tested from a variety of tissues (including skin, blood, and hair).The mutation is not found in either the mother or the father.Most likely, this is a new _______ mutation that occurred in _______.

Question

Quizplus · Accepted Answer

Since the mutation appears in all of the cells tested from various tissues, it suggests that the mutation is in the germline of the child. As the mutation is not found in either parent, it must have occurred spontaneously during gamete formation in one of the parents. This means that the mutation is a novel germline mutation.

Sequencing of a Child's Genomic DNA Reveals That the Child