People with sickle-cell disease have abnormal

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Sickle-cell disease is a genetic disorder that affects hemoglobin, the molecule that carries oxygen in red blood cells. People with sickle-cell disease have a mutation in the hemoglobin gene that results in abnormal hemoglobin molecules. These abnormal molecules can cause red blood cells to become rigid and assume a sickle shape, which can cause blockages in blood vessels, leading to pain and other complications.

People with Sickle-Cell Disease Have Abnormal