Phenylketonuria (PKU) and Duchenne muscular dystrophy (DMD) are both molecular diseases that are caused by mutations in particular genes, yet PKU is easier to treat than muscular dystrophy.Why?

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PKU is caused by a deficiency in the enzyme phenylalanine hydroxylase, which converts the amino acid phenylalanine to tyrosine. By restricting dietary intake of phenylalanine, the toxic buildup of phenylalanine in the body can be prevented, effectively managing the condition. Duchenne muscular dystrophy, on the other hand, involves a mutation in the dystrophin gene, affecting muscle function, and does not have a simple dietary treatment.

Phenylketonuria (PKU) and Duchenne Muscular Dystrophy (DMD) Are Both Molecular