Excess Numbers of the CGG Triplets in the FMR1 Gene

Excess numbers of the CGG triplets in the FMR1 gene lead to clinical symptoms, including mental retardation, because _______, which in turn contributes to death of nerve cells.

A) triplets bind to mRNAs of other genes
B) cytosines in the repeats are more likely to be methylated, which inhibits transcription of the gene
C) triplets cause the FMR1-encoded enzyme to be nonfunctional
D) triplets make the gene so large that its mRNA cannot be transported properly
E) triplets cause the protein to fold incorrectly