Refer to the figure. In Huntington's disease (HD) triplicate repeats of CAG in the huntingtin gene (HTT) cause a neurodegenerative disease that has a typical age of onset of between 30 and 50 years.A 38-year-old father has been diagnosed with HD.He and his wife are concerned that their four children may develop the disease, so they have the entire family undergo genetic testing.The HTT allele from each family member's DNA sample is amplified using PCR, and the products are then separated using gel electrophoresis.In the figure, the markers on the left side indicate how many triplicate repeats of CAG are in the HTT allele control samples.A person with 40 CAG repeats has a strong possibility of developing HD.When a parent has enough CAG repeats to cause HD, the disease is inherited in an autosomal dominant pattern.According to the results shown, which two of the children have a strong possibility of developing HD?

Question

Refer to the figure.  In Huntington's disease (HD) triplicate repeats of CAG in the huntingtin gene (HTT) cause a neurodegenerative disease that has a typical age of onset of between 30 and 50 years.A 38-year-old father has been diagnosed with HD.He and his wife are concerned that their four children may develop the disease, so they have the entire family undergo genetic testing.The HTT allele from each family member's DNA sample is amplified using PCR, and the products are then separated using gel electrophoresis.In the figure, the markers on the left side indicate how many triplicate repeats of CAG are in the HTT allele control samples.A person with >40 CAG repeats has a strong possibility of developing HD.When a parent has enough CAG repeats to cause HD, the disease is inherited in an autosomal dominant pattern.According to the results shown, which two of the children have a strong possibility of developing HD?

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The Answer of Refer to the figure.  In Huntington's disease (HD) triplicate repeats of CAG in the huntingtin gene (HTT) cause a neurodegenerative disease that has a typical age of onset of between 30 and 50 years.A 38-year-old father has been diagnosed with HD.He and his wife are concerned that their four children may develop the disease, so they have the entire family undergo genetic testing.The HTT allele from each family member's DNA sample is amplified using PCR, and the products are then separated using gel electrophoresis.In the figure, the markers on the left side indicate how many triplicate repeats of CAG are in the HTT allele control samples.A person with >40 CAG repeats has a strong possibility of developing HD.When a parent has enough CAG repeats to cause HD, the disease is inherited in an autosomal dominant pattern.According to the results shown, which two of the children have a strong possibility of developing HD?

Refer to the Figure