The most widely used treatment for PKU consists of

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The correct treatment for PKU is restricting the substrate, which means restricting the intake of phenylalanine. This is achieved through a special diet low in phenylalanine, which helps prevent the buildup of toxic levels of phenylalanine in the blood and brain. This has been the most widely used and effective treatment for PKU. Supplying a missing protein (A) is not an effective treatment because the problem in PKU is not a lack of protein, but the inability to break down phenylalanine. In vivo gene therapy (B) and ex vivo gene therapy (C) are potential treatments for PKU, but they are still in the experimental stages and not widely used yet. Providing metabolic inhibitors (D) is not an effective treatment because it does not address the underlying problem of excessive phenylalanine buildup.

The Most Widely Used Treatment for PKU Consists of